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Article

Genes involved in innate immunity associated with asbestos-related fibrotic changes.

Occupational and environmental medicine - 1 Jan 2014

Kukkonen Mari K, Vehmas Tapio, Piirilä Päivi, Hirvonen Ari

Abstract excerpt

OBJECTIVES: To determine whether genetic polymorphisms in several candidate genes related to innate immunity and protease-antiprotease balance modify individual susceptibility to develop asbestos-related fibrotic pleuropulmonary changes. METHODS: Sixteen polymorphisms from nine genes (NLRP3, CARD8, TNF, TGFB1, GC, MMP1, MMP9, MMP12 and TIMP2) were genotyped from 951 Finnish asbestos-exposed workers. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24142982
DOI: 10.1136/oemed-2013-101555
PMCID: PMC3888604

Genes

NLRP3
TGFB1
CARD8
TIMP2
MMP1
MMP12
MMP9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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