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Article

Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study.

PloS one - 1 Jan 2015

Weng Shaofan, Wang Lihua, Rong Yi, Liu Yuewei, Wang Xin, Guan Hongyu, Chen Weihong

Abstract excerpt

OBJECTIVES: To evaluate the effects of the interactions between polymorphisms in Nalp3, caspase-1, and interleukin(IL)-1β genes and occupational dust exposure on the risk of silicosis. METHODS: We conducted a population-based case-control study in a large iron mine in China. Between January 2006 and December 2009, we identified 179 patients with silicosis to evaluate as cases and 201 individuals without silicosis...

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Identifiers

PMID: 26496436
DOI: 10.1371/journal.pone.0140952
PMCID: PMC4619690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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