Article
Genetic susceptibility to progressive massive fibrosis in coal miners.
The European respiratory journal - 1 Jun 2008
Yucesoy B, Johnson V J, Kissling G E, Fluharty K, Kashon M L, Slaven J, Germolec D, Vallyathan V, Luster M I
Abstract excerpt
Progressive massive fibrosis (PMF) is a chronic interstitial lung disease with a complex aetiology that can occur after cumulative dust exposure. A case-control study was conducted to test the hypothesis that single nucleotide polymorphisms (SNPs) within genes involved in inflammatory and fibrotic processes modulate the risk of PMF development. The study population consisted of 648 underground coal miners...
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