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Article

Cellular and Molecular Basis of the Asbestos-related Diseases

1 Feb 1991

Abstract excerpt

Asbestosis is an inflammatory and fibrotic process of the alveolar structures mediated, at least in part, by cytokines released by "activated" alveolar macrophages. The process of phagocytosis and "activation" of alveolar macrophages is poorly understood. Are all macrophages activated or only subpopulations? Which cytokines are up-regulated? How does the local milieu modulate profibrotic and antifibrotic...

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Identifiers

PMID: 1990961
DOI: 10.1164/ajrccm/143.2.408

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