HapMap-based study identifies risk sub-region on chromosome 19q13.3 in relation to lung cancer among Chinese.

doi:10.1016/j.canep.2013.09.016

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HapMap-based study identifies risk sub-region on chromosome 19q13.3 in relation to lung cancer among Chinese.

Cancer epidemiology - 1 Dec 2013

Yin Jiaoyang, Vogel Ulla, Wang Huiwen, Ma Yegang, Wang Chunhong, Liang Duohong, Liu Jian, Yue Li, Zhao Yudan, Ma Jian

Abstract excerpt

BACKGROUND: Chromosome 19q13.3 has been identified as one of the regions that associate with cancer risk in previous studies. METHODS: We systematically examined the 70.772kb region comprising four genes on chromosome 19q13.3 among Chinese using the haplotype-tagging SNP (htSNP) approach and the HapMap platform. The study involved 339 lung cancer cases and 358 non-cancer controls. Two htSNPs (rs1046282 and...

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PMID: 24140460
DOI: 10.1016/j.canep.2013.09.016

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ERCC1
ERCC2

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