Article
Genome-wide haplotype association study identifies risk genes for non-small cell lung cancer.
Journal of theoretical biology - 7 Nov 2018
Teng Yanbo, Ding Yanjun, Zhang Mingming, Chen Xinren, Wang Xizi, Yu Hang, Liu Chonghui, Lv Hongchao, Zhang Ruijie
Abstract excerpt
Lung cancer is the leading cause of cancer-related death worldwide. Most lung cancer is non-small cell lung cancer (NSCLC), in which malignant cells form in the lung epithelium. Mutations in multiple genes and environmental factors both contribute to NSCLC, and although some NSCLC susceptibility genes have been characterized, the pathogenesis of this disease remains unclear. To identify genes conferring NSCLC...
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