Article
A functional variant at 19q13.3, rs967591G>A, is associated with shorter survival of early-stage lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2013
Jeon Hyo-Sung, Jin Guang, Kang Hyo-Gyoung, Choi Yi Young, Lee Won Kee, Choi Jin Eun, Bae Eun Young, Yoo Seung Soo, Lee Shin Yup, Lee Eung Bae, Kim Young Tae, Lee Jaehee, Cha Seung-Ick, Kim Chang Ho, Jheon Sanghoon, Kim In San, Park Jae Yong
Abstract excerpt
PURPOSE: This study was conducted to investigate the associations between single-nucleotide polymorphisms (SNP) in 19q13.3 and survival of patients with early-stage non-small cell lung cancer (NSCLC), and to define the causative functional SNP of the association. EXPERIMENTAL DESIGN: A two-stage study design was used to evaluate five SNPs in relation to survival outcomes in 328 patients and then to validate the...
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