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Article

TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population.

Biomedical journal - 1 Feb 2022

Yin Jiaoyang, Hou Wei, Vogel Ulla, Li Xinxin, Ma Yegang, Wang Chunhong, Wang Huiwen, Sun Zhenxiang

Abstract excerpt

BACKGROUND: TP53 encodes a tumor suppressor protein containing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. The effect of TP53 inactivation is well-known, and genetically determined smaller variations in TP53 activity are related to cancer. Lung cancer causes the highest rates of morbidity and mortality in the world. Epidemiology studies have assessed the association of TP53...

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Identifiers

PMID: 35351459
DOI: 10.1016/j.bj.2021.01.006
PMCID: PMC9133261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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