Article
Fine-mapping markers of lung cancer susceptibility in a sub-region of chromosome 19q13.3 among Chinese.
Oncotarget - 20 Sept 2016
Yin Jiaoyang, Wang Huiwen, Vogel Ulla, Wang Chunhong, Ma Yegang, Hou Wei, Zhang Ying, Guo Li, Li Xinxin
Abstract excerpt
Linkage disequilibrium-mapping studies in Caucasians have indicated anassociation of Chr19q13.3 sub-region spanning ERCC2, PPP1R13L, CD3EAP and ERCC1 with several cancers. To refine the region of association and identify potential causal variations among Asians, we performed a fine-mapping study using 32 (39) SNPs in a 71.654kb sub-region. The study included 384 Chinese lung cancer cases and 387 controls. Seven...
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