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19p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese.

Chemico-biological interactions - 1 Nov 2017

Hou Wei, Yin Jiaoyang, Vogel Ulla, Sun Zhenxiang, Liang Duohong

Abstract excerpt

Lung cancer is the most common cause of cancer-related mortality worldwide. The GADD45 gene family plays important roles in a variety of the responses to cell injury including cell cycle checkpoints, apoptosis, DNA repair and anti-tumor immunity. The 19p13.3-GADD45B encoded protein product is involved in apoptosis and inhibiting tumor growth. To evaluate the association of 19p13.3-GADD45B common variants and lung...

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PMID: 28870783
DOI: 10.1016/j.cbi.2017.08.018

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