Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acceleration of adipogenic differentiation via acetylation of malate dehydrogenase 2.

Biochemical and biophysical research communications - 8 Nov 2013

Kim Eun Young, Han Baek Soo, Kim Won Kon, Lee Sang Chul, Bae Kwang-Hee

Abstract excerpt

Previously, we identified proteins showing a differential acetylation pattern during adipogenic differentiation. Here, we examined the role of malate dehydrogenase 2 (MDH2) acetylation in the adipogenesis of 3T3-L1 preadipocytes. The acetylation level of MDH2 showed a dramatic increase during adipogenesis. The overexpression of wild-type MDH2 induced the significant acceleration of adipogenic differentiation. On...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3-L1 Cells
Share to Acetylation
Share to Adipocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adipogenesis

Share to Extracellular Space

Share to Glucose

Share to Malate Dehydrogenase

Source

Identifiers

PMID: 24134846
DOI: 10.1016/j.bbrc.2013.10.016

Genes

MDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acceleration of adipogenic differentiation via acetylation of malate dehydrogenase 2.PMID 24134846Read ↗

Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity.Semantic proximity Read ↗

Acetylation and deacetylation of histone in adipocyte differentiation and the potential significance in cancerSemantic proximity Read ↗

Regulation of Thermogenic Adipocyte Differentiation and Adaptive Thermogenesis Through Histone AcetylationSemantic proximity Read ↗

Epigenetic Regulation of Adipogenesis by Histone-Modifying EnzymesSemantic proximity Read ↗

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.Semantic proximity Read ↗

Histone Deacetylase 3 Regulates Adipocyte Phenotype at Early Stages of Differentiation.Semantic proximity Read ↗

AZIN2-dependent polyamine metabolism determines adipocyte progenitor fate and protects against obesity and dysmetabolismSemantic proximity Read ↗

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.Semantic proximity Read ↗

Coordination between metabolic transitions and gene expression by NAD <sup>+</sup> availability during adipogenic differentiation in human cellsSemantic proximity Read ↗

HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription.Semantic proximity Read ↗

Increased ATP citrate lyase affects maternal diabetes-induced neural tube defects by promoting the H3K27ac modification through the Gadd45g pathwaySemantic proximity Read ↗

Down-regulation of ABHD2 Gene Induced Emphysema by Accelerating Triglyceride DepositionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.