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Article

Histone Deacetylase 3 Regulates Adipocyte Phenotype at Early Stages of Differentiation.

International journal of molecular sciences - 27 Aug 2021

Cricrí Dalma, Coppi Lara, Pedretti Silvia, Mitro Nico, Caruso Donatella, De Fabiani Emma, Crestani Maurizio

Abstract excerpt

Obesity is a condition characterized by uncontrolled expansion of adipose tissue mass resulting in pathological weight gain. Histone deacetylases (HDACs) have emerged as crucial players in epigenetic regulation of adipocyte metabolism. Previously, we demonstrated that selective inhibition of class I HDACs improves white adipocyte functionality and promotes the browning phenotype of murine mesenchymal stem cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34502211
DOI: 10.3390/ijms22179300
PMCID: PMC8430751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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