Article
Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity.
Journal of lipid research - 1 Sept 2012
Kim Eun Young, Kim Won Kon, Kang Hyo Jin, Kim Jeong-Hoon, Chung Sang J, Seo Yeon Soo, Park Sung Goo, Lee Sang Chul, Bae Kwang-Hee
Abstract excerpt
Acetylation is one of the most crucial post-translational modifications that affect protein function. Protein lysine acetylation is catalyzed by acetyltransferases, and acetyl-CoA functions as the source of the acetyl group. Additionally, acetyl-CoA plays critical roles in maintaining the balance between carbohydrate metabolism and fatty acid synthesis. Here, we sought to determine whether lysine acetylation is...
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