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The Leu72Met polymorphism of the GHRL gene prevents the development of diabetic nephropathy in Chinese patients with type 2 diabetes mellitus.

Molecular and cellular biochemistry - 1 Feb 2014

Zhuang Langen, Li Ming, Yu Changhua, Li Can, Zhao Mingming, Lu Ming, Zheng Taishan, Zhang Rong, Zhao Weijing, Bao Yuqian, Xiang Kunsan, Jia Weiping, Wang Niansong, Liu Limei

Abstract excerpt

The preproghrelin (GHRL) Leu72Met polymorphism (rs 696217) is associated with obesity, reduced glucose-induced insulin secretion in healthy or diabetic subjects, and reduced serum creatinine (Scr) levels in type 2 diabetes. We evaluated the association of the Leu72Met polymorphism with measures of insulin sensitivity in non-diabetic control individuals and type 2 diabetics, and whether this variation contributes...

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Identifiers

PMID: 24132517
DOI: 10.1007/s11010-013-1865-6

Genes

GHRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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