Article
Study of IL4-590C/T and IL6-174G/C Gene Polymorphisms in Type 2 Diabetic Patients With Chronic Kidney Disease in North Indian Population.
Journal of cellular biochemistry - 1 Jul 2017
Neelofar Km, Ahmad Jamal, Ahmad Arif, Alam Khursheed
Abstract excerpt
To explore the associations between potential functional promoter polymorphisms in pro-inflammatory and anti-inflammatory (IL-4(-590C/T) and IL-6(-174G/C) cytokine genes, and kidney dysfunction in North Indian type 2 diabetic subjects with chronic kidney disease. A total of 150 subjects aged 25-75 year were included in this study. The glomerular filtration rate (GFR) and serum creatinine were estimated. PCR was...
Topics
- Adult
- Aged
- Asian People
- Creatinine
- Diabetes Mellitus, Type 2
- Electrophoresis, Agar Gel
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Glomerular Filtration Rate
- Humans
- Interleukin-4