Arg913Gln of SLC12A3 gene promotes development and progression of end-stage renal disease in Chinese type 2 diabetes mellitus.

doi:10.1007/s11010-017-3120-z

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Article

Arg913Gln of SLC12A3 gene promotes development and progression of end-stage renal disease in Chinese type 2 diabetes mellitus.

Molecular and cellular biochemistry - 1 Jan 2018

Zhang Rong, Zhuang Langen, Li Ming, Zhang Juan, Zhao Weijing, Ge Xiaoxu, Chen Yating, Wang Feng, Wang Niansong, Bao Yuqian, Liu Limei, Liu Yanjun, Jia Weiping

Abstract excerpt

Whether the Arg913Gln variation (rs11643718, G/A) of SLC12A3 contributes to diabetic nephropathy (DN) remains controversial. We undertook a case-control study to evaluate the association of the SLC12A3-Arg913Gln variation with the risk of end-stage renal disease (ESRD) in Chinese type 2 diabetes mellitus (T2DM) patients undergoing hemodialysis, and analyzed the genotype-phenotype interaction. Unrelated Chinese...

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PMID: 28744814
DOI: 10.1007/s11010-017-3120-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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