Article
Preproghrelin Leu72Met polymorphism predicts a lower rate of developing renal dysfunction in type 2 diabetic nephropathy.
European journal of endocrinology - 1 Jul 2006
Lee Dae-Yeol, Kim Sun-Young, Jo Dae-Sun, Hwang Pyoung Han, Kang Kyung Pyo, Lee Sik, Kim Won, Park Sung Kwang
Abstract excerpt
OBJECTIVE: Ghrelin is a novel peptide hormone, which exerts somatotropic, orexigenic and adipogenic effects. Recent studies have shown that the preproghrelin Leu72Met polymorphism is associated with serum creatinine (Scr) concentration in type 2 diabetes; 72Met carriers exhibited lower Scr levels as compared with the 72Met non-carriers. We hypothesized that the preproghrelin Leu72Met polymorphism is associated...
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