Article
Leu72Met polymorphism of GHRL gene decreases susceptibility to type 2 diabetes mellitus in a Mexican population.
BMC endocrine disorders - 22 Jul 2020
Rivera-León Edgar Alfonso, Llamas-Covarrubias Mara Anaís, Sánchez-Enríquez Sergio, Martínez-López Erika, González-Hita Mercedes, Llamas-Covarrubias Iris Monserrat
Abstract excerpt
BACKGROUND: Type 2 diabetes mellitus (T2D) is the most frequent type of diabetes. It has a multifactorial etiology, affecting millions of people worldwide. Ghrelin gene (GHRL) encodes the ghrelin peptide, which promotes food intake, induces body weight and adipogenesis. Several single nucleotide polymorphisms (SNPs) in GHRL gene have been associated with metabolic diseases. A protective effect of the Leu72Met...
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