Article
Preproghrelin Leu72Met polymorphism is not associated with type 2 diabetes mellitus.
Metabolism: clinical and experimental - 1 Mar 2006
Kim Sun-Young, Jo Dae-Sun, Hwang Pyoung Han, Park Ji Hyun, Park Sung Kwang, Yi Ho Keun, Lee Dae-Yeol
Abstract excerpt
Ghrelin is a novel gut-brain peptide, which exerts somatotropic, orexigenic, and adipogenic effects. Genetic variants of ghrelin have been associated with both obesity and insulin metabolism. In this study, we determined a role of preproghrelin Leu72Met polymorphism on type 2 diabetes mellitus and its relationship to variables studied. Genotypes were assessed by polymerase chain reaction. Frequencies of the...
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