Article
Integrative functional linear model for genome-wide association studies with multiple traits.
Biostatistics (Oxford, England) - 13 Apr 2022
Li Yang, Wang Fan, Wu Mengyun, Ma Shuangge
Abstract excerpt
In recent biomedical research, genome-wide association studies (GWAS) have demonstrated great success in investigating the genetic architecture of human diseases. For many complex diseases, multiple correlated traits have been collected. However, most of the existing GWAS are still limited because they analyze each trait separately without considering their correlations and suffer from a lack of sufficient...
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