Article
Molecular characterization and functional analysis of murine interleukin 4 receptor allotypes.
The Journal of experimental medicine - 3 Nov 1997
Schulte T, Kurrle R, Röllinghoff M, Gessner A
Abstract excerpt
The murine interleukin 4 receptor (IL-4R) exists as a transmembrane protein transducing pleiotropic IL-4 functions, or as soluble (s)IL-4-binding molecule with potent immunoregulatory effects. In this study we identified and characterized a murine IL-4R allotype. Sequence analysis of the IL-4R cD...
Topics
- Alleles
- Amino Acid Substitution
- Animals
- Antibodies, Monoclonal
- Antibody Specificity
- Base Sequence
- Binding Sites, Antibody
- Cell Membrane
- DNA Restriction Enzymes
- Epitope Mapping
- Extracellular Space
- Female
- Glycosylation
- Kinetics
- Mice
- Mice, Inbred AKR
- Mice, Inbred BALB C
- Mice, Inbred C3H