Article
A stimulatory monoclonal antibody detecting T cell receptor diversity among idiotype-specific, major histocompatibility complex-restricted T cell clones.
European journal of immunology - 1 Oct 1990
Bogen B, Lauritzsen G F, Weiss S
Abstract excerpt
A panel of independent BALB/c T cell clones responding to a peptide of the lambda 2(315) immunoglobulin light chain (residues 91-101), in the context of I-Ed, has previously been described. A monoclonal antibody (mAb; GB113) to the T cell receptor (TcR) of one of the clones, 4B2A1 (V alpha 1, J alpha 19; V beta 8.2, D beta 1.1, J beta 1.2) precipitates the alpha/beta heterodimer from 4B2A1. However, GB113 does...
Topics
- Animals
- Antibodies, Monoclonal
- Antibody Specificity
- Clone Cells
- Epitopes
- Genetic Variation
- Histocompatibility Antigens
- Interferon-gamma
- Interleukin-2
- Interleukin-3
- Lymphocyte Activation
