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Article

Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a.

Journal of virological methods - 1 Jan 2014

Kylefjord Helen, Danielsson Axel, Sedig Susanne, Belda Oscar, Wiktelius Daniel, Vrang Lotta, Targett-Adams Paul

Abstract excerpt

Although hepatitis C virus (HCV) is a pathogen of global significance, experimental therapies in current clinical development include highly efficacious all-oral combinations of HCV direct-acting antivirals (DAAs). If approved for use, these new treatment regimens will impact dramatically upon our capacity to eradicate HCV in the majority of virus-infected patients. However, recent data from late-stage clinical...

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Identifiers

PMID: 24120570
DOI: 10.1016/j.jviromet.2013.09.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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