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Article

DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus

14 Oct 2013

Abstract excerpt

Systemic lupus erythematosus (SLE) disease is an autoimmune disease of unknown aetiology that affects predominantly women of child bearing age. Since previous studies, including ours, have demonstrated that CD4+ T cells and B cells from SLE patients are defective in their ability to methylate their DNA upon antigen stimulation, the aim of this study was to investigate whether DNA demethylation affects the...

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PMID: 24117194
DOI: 10.3109/08916934.2013.826207

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