Article
On individual genome-wide association studies and their meta-analysis.
Human genetics - 1 Mar 2014
Pei Yu-Fang, Zhang Lei, Papasian Christopher J, Wang Yu-Ping, Deng Hong-Wen
Abstract excerpt
Individual genome-wide association (GWA) studies and their meta-analyses represent two approaches for identifying genetic loci associated with complex diseases/traits. Inconsistent findings and non-replicability between individual GWA studies and meta-analyses are commonly observed, hence posing the critical question as to how to interpret their respective results properly. In this study, we performed a series of...
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