Article
Meta-analysis of genetic association studies and adjustment for multiple testing of correlated SNPs and traits.
Genetic epidemiology - 1 Nov 2010
Conneely Karen N, Boehnke Michael
Abstract excerpt
Meta-analysis has become a key component of well-designed genetic association studies due to the boost in statistical power achieved by combining results across multiple samples of individuals and the need to validate observed associations in independent studies. Meta-analyses of genetic association studies based on multiple SNPs and traits are subject to the same multiple testing issues as single-sample studies,...
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