Article
Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse.
Journal of human genetics - 1 Nov 2009
Nakaoka Hirofumi, Inoue Ituro
Abstract excerpt
Meta-analysis is a useful tool to increase the statistical power to detect gene-disease associations by combining results from the original and subsequent replication studies. Recently, consortium-based meta-analyses of several genome-wide association (GWA) data sets have discovered new susceptib...
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