Article
Methods for meta-analysis of genetic data.
Current protocols in human genetics - 1 Jan 2013
Lunetta Kathryn L
Abstract excerpt
Modern genetic association studies, using genome-wide genotype data, are often underpowered. Meta-analyses of multiple studies performing genome-wide genotyping improve power and have led to the identification of thousands of genotype-trait associations. This unit provides an overview of the key concepts required for genetic meta-analyses, and presents strategic approaches and key decisions that must be made in...
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