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Article

Does an Alzheimer's disease susceptibility gene influence the cognitive effects of cancer therapy?

Pediatric blood & cancer - 1 Oct 2014

Caselli Richard J

Abstract excerpt

The apolipoprotein E (APOE) e4 allele is the most prevalent genetic risk factor for Alzheimer's disease (AD). APOE e4 carriers suffer greater morbidity from head trauma, stroke, and carbon monoxide poisoning, yet possible interactions between APOE genotype and cancer therapy on cognition are unclear. Neuropathological and biomarker studies of young asymptomatic APOE e4 carriers that show elevated neocortical...

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Source

Identifiers

PMID: 24106134
DOI: 10.1002/pbc.24768

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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