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Article

Impact of APOE Genotype on Neurocognition Following Conformal Whole Brain Radiotherapy for Brain Metastases: A Post hoc Analysis of Phase II Randomized Trial

2025-05-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> The genetic risk of radiotherapy-induced cognitive decline (RICD) in patients undergoing whole-brain radiotherapy (WBRT) has not been clearly established. Apolipoprotein E (APOE) polymorphisms, known to influence cognitive aging and Alzheimer’s disease risk, may also modulate neurocognitive outcomes after cranial irradiation. This post-hoc analysis investigate...

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Literature Corpus work
b4a91642-a04f-5e23-bcf8-b95b59b88ecc
DOI
10.21203/rs.3.rs-6431871/v1
Open publication

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Impact of APOE Genotype on Neurocognition Following Conformal Whole Brain Radiotherapy for Brain Metastases: A Post hoc Analysis of Phase II Randomized TrialDOI 10.21203/rs.3.rs-6431871/v1
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