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Article

Apolipoprotein E genotype and gender influence response to tacrine therapy.

Annals of the New York Academy of Sciences - 16 Dec 1996

Farlow M R, Lahiri D K, Poirier J, Davignon J, Hui S

Abstract excerpt

Our objective is to evaluate the effects of apolipoprotein E genotype (APOE) on clinical response to treatment with tacrine, in patients with Alzheimer's disease (AD). Only 25 to 50% of patients with AD, depending on dose and design, have been responders in previous tacrine trials. AD autopsy stu...

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Source

Identifiers

PMID: 8993489
DOI: 10.1111/j.1749-6632.1996.tb32603.x

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8993489-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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