Article
The impact of APOE and smoking history on cognitive function in older, long-term breast cancer survivors.
Journal of cancer survivorship : research and practice - 1 Apr 2024
Ahles Tim A, Orlow Irene, Schofield Elizabeth, Li Yuelin, Ryan Elizabeth, Root James C, Patel Sunita K, McNeal Katrazyna, Gaynor Alexandra, Tan Heidi, Katheria Vani, Vazquez Jessica, Corrales-Guerrero Sergio, Sadeghi Keimya, Traina Tiffany, Hurria Arti
Abstract excerpt
PURPOSE: This study aims to determine whether older breast cancer survivors score lower on neuropsychological tests compared to matched non-cancer controls and to test the hypotheses that survivors who were APOE ε4 carriers would have the lowest cognitive performance but that smoking history would decrease the negative effect of ε4 on cognition. METHODS: Female breast cancer survivors who had been diagnosed and...
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