Article
The spore differentiation pathway in the enteric pathogen Clostridium difficile.
PLoS genetics - 1 Jan 2013
Pereira Fátima C, Saujet Laure, Tomé Ana R, Serrano Mónica, Monot Marc, Couture-Tosi Evelyne, Martin-Verstraete Isabelle, Dupuy Bruno, Henriques Adriano O
Abstract excerpt
Endosporulation is an ancient bacterial developmental program that culminates with the differentiation of a highly resistant endospore. In the model organism Bacillus subtilis, gene expression in the forespore and in the mother cell, the two cells that participate in endospore development, is governed by cell type-specific RNA polymerase sigma subunits. σ(F) in the forespore, and σ(E) in the mother cell control...
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