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Article

High-Throughput Genetic Screens Identify a Large and Diverse Collection of New Sporulation Genes in Bacillus subtilis.

PLoS biology - 1 Jan 2016

Meeske Alexander J, Rodrigues Christopher D A, Brady Jacqueline, Lim Hoong Chuin, Bernhardt Thomas G, Rudner David Z

Abstract excerpt

The differentiation of the bacterium Bacillus subtilis into a dormant spore is among the most well-characterized developmental pathways in biology. Classical genetic screens performed over the past half century identified scores of factors involved in every step of this morphological process. More recently, transcriptional profiling uncovered additional sporulation-induced genes required for successful spore...

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PMID: 26735940
DOI: 10.1371/journal.pbio.1002341
PMCID: PMC4703394

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