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Development of a dual fluorescent reporter system in <i>Clostridioides difficile</i> reveals a division of labor between virulence and transmission gene expression

2022-03-04

Abstract excerpt

<h4>ABSTRACT</h4> The bacterial pathogen Clostridioides difficile causes gastroenteritis through its production of toxins and transmits disease through its production of resistant spores. Toxin and spore production are energy-expensive processes that are regulated by multiple transcription factors in response to many nutritional inputs. While toxin and sporulation genes are both heterogeneously expressed in only...

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Literature Corpus work
23c8cbe4-6dcb-5f5c-87f5-571bfc466831
DOI
10.1101/2022.03.03.482933
Open publication

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