Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner.

PLoS pathogens - 1 Aug 2024

Nerber Hailee N, Baloh Marko, Brehm Joshua N, Sorg Joseph A

Abstract excerpt

Clostridioides difficile is a pathogen whose transmission relies on the formation of dormant endospores. Spores are highly resilient forms of bacteria that resist environmental and chemical insults. In recent work, we found that C. difficile SspA and SspB, two small acid-soluble proteins (SASPs), protect spores from UV damage and, interestingly, are necessary for the formation of mature spores. Here, we build...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Clostridioides difficile
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Spores, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 39213448
DOI: 10.1371/journal.ppat.1012507
PMCID: PMC11392383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner.PMID 39213448Read ↗

Differential requirements for conserved peptidoglycan remodeling enzymes during Clostridioides difficile spore formationSemantic proximity Read ↗

A cortex-specific penicillin-binding protein contributes to heat resistance in Clostridioides difficile sporesSemantic proximity Read ↗

Characterization of Clostridium difficile Spores Lacking Either SpoVAC or Dipicolinic Acid Synthetase.Semantic proximity Read ↗

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficileSemantic proximity Read ↗

Regulation of Clostridium difficile Spore Formation by the SpoIIQ and SpoIIIA Proteins.Semantic proximity Read ↗

SpoIVA and SipL Are Clostridium difficile Spore Morphogenetic ProteinsSemantic proximity Read ↗

Proteomic and Genomic Characterization of Highly Infectious <i>Clostridium difficile</i> 630 SporesSemantic proximity Read ↗

Regulation of Clostridium difficile spore germination by the CspA pseudoprotease domain.Semantic proximity Read ↗

Identification of ClpP Dual Isoform Disruption as an Antisporulation Strategy for Clostridioides difficile.Semantic proximity Read ↗

SpoIIID ‐mediated regulation of σ K function during C lostridium difficile sporulationSemantic proximity Read ↗

CD25890, a conserved protein that modulates sporulation initiation in Clostridioides difficileSemantic proximity Read ↗

Whole-genome analysis of sporulation and germination in Clostridium difficileSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.