Article
Regulation of Clostridium difficile Spore Formation by the SpoIIQ and SpoIIIA Proteins.
PLoS genetics - 1 Oct 2015
Fimlaid Kelly A, Jensen Owen, Donnelly M Lauren, Siegrist M Sloan, Shen Aimee
Abstract excerpt
Sporulation is an ancient developmental process that involves the formation of a highly resistant endospore within a larger mother cell. In the model organism Bacillus subtilis, sporulation-specific sigma factors activate compartment-specific transcriptional programs that drive spore morphogenesis. σG activity in the forespore depends on the formation of a secretion complex, known as the "feeding tube," that...
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