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Differential requirements for conserved peptidoglycan remodeling enzymes during Clostridioides difficile spore formation

1 Aug 2018

Abstract excerpt

Spore formation is essential for the bacterial pathogen and obligate anaerobe, Clostridioides (Clostridium) difficile, to transmit disease. Completion of this process depends on the mother cell engulfing the developing forespore, but little is known about how engulfment occurs in C. difficile. In Bacillus subtilis, engulfment is mediated by a peptidoglycan degradation complex consisting of SpoIID, SpoIIP and...

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PMID: 30066347
DOI: 10.1111/mmi.14090

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