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Article

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes.

Nature - 1 Jan 2000

Mattaj I W, Lienhard S, Jiricny J, De Robertis E M

Abstract excerpt

Enhancers are eukaryotic promoter elements that increase transcriptional efficiency in a manner relatively independent of their position and orientation with respect to a nearby gene. There is growing evidence that enhancer action is mediated by transacting factors, but the mode of action of these factors is not yet known. We report here on the Xenopus U2 gene promoter, which contains two sequence elements. The...

Topics

Animals
Base Sequence
Enhancer Elements, Genetic
Genes, Regulator
Immunoglobulin Heavy Chains
Immunoglobulin Light Chains
Mutation
Promoter Regions, Genetic
RNA
RNA, Small Nuclear
Simian virus 40

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factors

Transcription, Genetic

Xenopus

Source

Identifiers

PMID: 2409453
DOI: 10.1038/316163a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2409453-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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