Article
Prnp gene and cerebellum volume in patients with refractory mesial temporal lobe epilepsy.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Feb 2014
Valadão Michelle N, Coimbra Erica R, Landemberger Michele C, Velasco Tonicarlo R, Terra Vera C, Wichert-Ana Lauro, Alexandre Veriano, Araújo David, Guarnieri Ricardo, Martins Vilma R, Santos Antônio Carlos, Sakamoto Américo C, Walz Roger
Abstract excerpt
The cellular prion protein, encoded by Prnp gene, is involved in neuroprotection, neuroplasticity and neurodevelopment. The variant allele Valine at codon 129 of the Prnp was associated with decreased brain volume in healthy volunteers and schizophrenic patients. We investigate the association between the cerebellum volume and the presence of variant allele Valine at codon 129 of the Prnp gene in patients with...
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