Article
Association between the M129V variant allele of PRNP gene and mild temporal lobe epilepsy in women.
Neuroscience letters - 21 Jun 2007
Labate Angelo, Manna Ida, Gambardella Antonio, Le Piane Emilio, La Russa Antonella, Condino Francesca, Cittadella Rita, Aguglia Umberto, Quattrone Aldo
Abstract excerpt
Specific variations in the prion protein gene (PRNP) are associated with, and prevalent in patients with intractable temporal lobe epilepsy (TLE) and influence the surgical outcome. We investigated whether or not the PRNP gene is a susceptibility gene in temporal lobe epileptic patients with mild epilepsy. We systematically screened the entire open reading frame of the PRNP gene and evaluated the genetic...
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