Article
Analysis of PRNP gene codon 129 polymorphism in the Greek population.
European journal of epidemiology - 1 Jan 2006
Saetta Angelica A, Michalopoulos Nikolaos V, Malamis George, Papanastasiou Polyanthi I, Mazmanian Niki, Karlou Maria, Kouzoupis Anastasios, Korkolopoulou Penelope, Patsouris Efstratios
Abstract excerpt
Creutzfeldt-Jakob disease (CJD) is a fatal transmissible neurodegenerative prion disease with a rapid progression comprising familial, sporadic, iatrogenic and variant forms. A polymorphism at codon 129 of PRNP gene has been implicated in the development of variant CJD. We examined Met/Val allele frequencies and the genotype distribution, with respect to the polymorphic codon 129 of PRNP gene in 348 healthy...
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