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Article

M129V variation in the prion protein gene and psychotic disorders: relationship to neuropsychological and psychopathological measures.

Journal of psychiatric research - 1 Nov 2007

Martorell Lourdes, Valero Joaquín, Mulet Begoña, Gutiérrez-Zotes Alfonso, Cortés Maria José, Jariod Manel, Pérez Modesto, Labad Antonio, Vilella Elisabet

Abstract excerpt

The methionine/valine polymorphism at position 129 in the prion protein gene, PRNP M129V, is a known risk factor for Creutzfeldt-Jakob disease (CJD). Psychiatric manifestations including psychosis are common in the early phase of CJD and it has therefore been hypothesized that the prion protein could be involved in psychotic disorders. Moreover, among the various hypothesized functions of the prion protein, a...

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Identifiers

PMID: 16949098
DOI: 10.1016/j.jpsychires.2006.07.003

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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M129V variation in the prion protein gene and psychotic disorders: relationship to neuropsychological and psychopathological measures.PMID 16949098Read ↗

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Is M129V of PRNP gene associated with Alzheimer's disease? A case-control study and a meta-analysis.Semantic proximity Read ↗

Analysis of PRNP gene codon 129 polymorphism in the Greek population.Semantic proximity Read ↗

Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

The influence of PRNP polymorphisms on human prion disease susceptibility: an update.Semantic proximity Read ↗

Methionine homozygosity at codon 129 in the prion protein is associated with white matter reduction and enlargement of CSF compartments in healthy volunteers and schizophrenic patients.Semantic proximity Read ↗

Codon 129 polymorphism of the PRNP gene in normal Polish population and in Creutzfeldt-Jakob disease, and the search for new mutations in PRNP gene.Semantic proximity Read ↗

Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease.Semantic proximity Read ↗

PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism.Semantic proximity Read ↗

The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population.Semantic proximity Read ↗

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