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Article

Dissecting the role of flagellar subunits in C. difficile mucosal colonization.

Journal of bacteriology - 18 Dec 2025

Biswas Baishakhi, Do Thi Van Thanh, Perdomo Justin G, Auchtung Jennifer M, Piepenbrink Kurt H

Abstract excerpt

Clostridioides difficile is a common cause of acute gastrointestinal (GI) inflammation in mammals, which can have detrimental effects on host health. C. difficile-associated disease requires the secretion of high-molecular-weight toxins after colonization of the GI tract. The molecular mechanisms of GI colonization by C. difficile include potential interactions with host cells and the mucus layer formed from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41283672
DOI: 10.1128/jb.00428-25
PMCID: PMC12713411

Genes

F3

Provenance

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