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Article

The role of flagella in Clostridium difficile pathogenicity.

Trends in microbiology - 1 May 2015

Stevenson Emma, Minton Nigel P, Kuehne Sarah A

Abstract excerpt

Clostridium difficile is widely publicised as a problem in the health-care system. Disruption of the normal gut microbiota by antibiotic therapy allows C. difficile to colonise the colon. On colonisation, C. difficile produces two toxins that lead to disease, with symptoms ranging from mild-to-severe diarrhoea, to fulminant and often fatal pseudomembranous colitis (PMC). How C. difficile establishes initial...

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Identifiers

PMID: 25659185
DOI: 10.1016/j.tim.2015.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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