Article
Tyrosine phosphorylation is essential for DSCAML1 to promote dendrite arborization of mouse cortical neurons.
Neuroscience letters - 25 Oct 2013
Cui Shaoqian, Lao Limin, Duan Jingzhu, Jin Guoxin, Hou Xu
Abstract excerpt
Dendritic self-avoidance is critical for appropriate dendrite arborization. We herein examined the role of Down syndrome cell adhesion molecule like-1 (DSCAML1) in regulating dendritic self-avoidance and that of tyrosine phosphorylation in mediating the effects of DSCAML1. Knocking down DSCAML1 in newborn mouse cortical neurons compromised dendritic self-avoidance as evidenced by dendritic fasciculation and...
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