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Article

Dscam Proteins Direct Dendritic Targeting through Adhesion.

Neuron - 3 Feb 2016

Tadros Wael, Xu Shuwa, Akin Orkun, Yi Caroline H, Shin Grace Ji-Eun, Millard S Sean, Zipursky S Lawrence

Abstract excerpt

Cell recognition molecules are key regulators of neural circuit assembly. The Dscam family of recognition molecules in Drosophila has been shown to regulate interactions between neurons through homophilic repulsion. This is exemplified by Dscam1 and Dscam2, which together repel dendrites of lamina neurons, L1 and L2, in the visual system. By contrast, here we show that Dscam2 directs dendritic targeting of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26844831
DOI: 10.1016/j.neuron.2015.12.026
PMCID: PMC4742784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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