Article
APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease.
Psychiatry research - 30 Dec 2013
Donix Markus, Burggren Alison C, Scharf Maria, Marschner Kira, Suthana Nanthia A, Siddarth Prabha, Krupa Allison K, Jones Michael, Martin-Harris Laurel, Ercoli Linda M, Miller Karen J, Werner Annett, von Kummer Rüdiger, Sauer Cathrin, Small Gary W, Holthoff Vjera A, Bookheimer Susan Y
Abstract excerpt
Across species structural and functional hemispheric asymmetry is a fundamental feature of the brain. Environmental and genetic factors determine this asymmetry during brain development and modulate its interaction with brain disorders. The e4 allele of the apolipoprotein E gene (APOE-4) is a risk factor for Alzheimer's disease, associated with regionally specific effects on brain morphology and function during...
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