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Article

New functional aspects of the atypical protein tyrosine phosphatase VHZ.

Biochemistry - 12 Nov 2013

Kuznetsov Vyacheslav I, Hengge Alvan C

Abstract excerpt

LDP3 (VHZ) is the smallest classical protein tyrosine phosphatase (PTP) known to date and was originally misclassified as an atypical dual-specificity phosphatase. Kinetic isotope effects with steady-state and pre-steady-state kinetics of VHZ and mutants with p-nitrophenol phosphate have revealed several unusual properties. VHZ is significantly more active than previously reported but remains one of the least...

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Identifiers

PMID: 24073992
DOI: 10.1021/bi400776z
PMCID: PMC3856698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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