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Article

PAQR-2 regulates fatty acid desaturation during cold adaptation in C. elegans.

PLoS genetics - 1 Jan 2013

Svensk Emma, Ståhlman Marcus, Andersson Carl-Henrik, Johansson Maja, Borén Jan, Pilon Marc

Abstract excerpt

C. elegans PAQR-2 is homologous to the insulin-sensitizing adiponectin receptors in mammals, and essential for adaptation to growth at 15°C, a low but usually acceptable temperature for this organism. By screening for novel paqr-2 suppressors, we identified mutations in genes involved in phosphatidylcholine synthesis (cept-1, pcyt-1 and sams-1) and fatty acid metabolism (ech-7, hacd-1, mdt-15, nhr-49 and sbp-1)....

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Identifiers

PMID: 24068966
DOI: 10.1371/journal.pgen.1003801
PMCID: PMC3772066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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